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ESB AI Lab

A California 501(c)(3) Nonprofit Research Organization

ESB AI Lab is now an independent nonprofit. We incorporated in California on April 22, 2026 and are recognized by the IRS as a 501(c)(3) tax-exempt organization. Support our mission →

ESB AI Lab is an independent nonprofit research organization developing computational methods in artificial intelligence, machine learning, and genomics to address challenges in food security, species conservation, climate resilience, human health, and language preservation.


Research Focus

View all research programs →

AI-Directed Breeding and Aquaculture

Computer vision and genomic approaches for sustainable agriculture and aquaculture, including AI-assisted sex determination in sturgeon.

Computer Vision for Conservation

Computational methods supporting the conservation and recovery of threatened and endangered species.

Climate and Disease Ecology

Climate-driven changes in vector-borne disease distribution and vector genomics.

Genome Evolution and RNA Biology

Biological adaptation to environmental change, RNA regulatory mechanisms, and structural variation in crops and model organisms.

Computational Pathology and Cancer Genomics

Machine learning and genomic analysis applied to human health.

Endangered Language Preservation

NLP, speech recognition, and AI-assisted OCR for endangered languages.

Edge AI for Field Research

Multi-sensor edge AI systems for real-time data collection in field and farm settings.

Open Science and Education

Accessible AI tools and educational programs broadening scientific participation.


Funding

Our research is supported by:

  • NSF ACCESS Computing Allocations

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We welcome collaborators, volunteers, and supporters at all levels. Whether you are a researcher, student, or community member, there are ways to contribute to our mission.

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news

Oct 03, 2026 ESB AI Lab receives IRS determination letter granting 501(c)(3) tax-exempt status. The Internal Revenue Service has recognized ESB AI Lab as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code, classified as a 509(a)(2) public charity. The determination is effective retroactive to the date of incorporation, April 22, 2026. All contributions to ESB AI Lab are tax-deductible to the extent permitted by law. The determination follows the Form 1023 application filed in July 2026 with the assistance of Foundation Group.
Sep 11, 2026 ESB AI Lab hosts its first public webinar, “Leveling Up Research with AI.” The free virtual session covered practical applications of artificial intelligence in scientific research. The recording is available on the ESB AI Lab YouTube channel.
Jul 24, 2026 ESB AI Lab submits Form 1023 application for federal 501(c)(3) tax-exempt status. The application, prepared by Foundation Group under the SureStart Complete package, was filed with the Internal Revenue Service seeking recognition as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code. Upon favorable determination, contributions to ESB AI Lab are expected to be tax-deductible retroactive to the date of incorporation, April 22, 2026. The organization was incorporated as a California Nonprofit Public Benefit Corporation for scientific, educational, and charitable purposes. Processing times for Form 1023 applications typically range from three to six months.
Jul 07, 2026 Executive Director Edwin Solares’s research on AI-assisted sex determination in endangered red abalone is featured by the San Diego Supercomputer Center. The study developed deep learning models trained on thousands of ultrasound images to identify abalone sex non-invasively, achieving approximately 86% accuracy with near-instantaneous results. Traditional methods require removing abalone from their shells, causing stress and potential injury. The work, conducted at UC San Diego using NSF ACCESS allocations on SDSC’s Expanse and Pittsburgh Supercomputing Center’s Bridges-2 systems, supports conservation hatcheries in selecting mature breeding candidates more efficiently. This research was completed prior to Dr. Solares’s appointment as Executive Director of ESB AI Lab.
Jul 06, 2026 ESB AI Lab launches its Education Programs page, featuring 22 hands-on training programs across four domains: bioinformatics, machine learning, infrastructure, and hardware. Offerings range from free public seminars to multi-day bootcamps in AI, scientific computing, computer vision, and genomics. Programs are designed for working researchers with contact hours ranging from 4 to 32 hours. An interest form is now live for prospective participants to indicate which programs they would like to see scheduled first. Program dates will be set based on demand, and scholarship support is available.

selected publications

  1. Front. AI
    Deep Learning Classification of Reproductive Tissue from Ultrasound: Sex Determination in Red Abalone (Haliotis rufescens)
    Edwin A. Solares, Anthony Tong, Sohyun Yoo, and 9 more authors
    Frontiers in Artificial Intelligence, 2026
  2. J Infect Dis
    PvGAP: Development of a Globally Applicable, Highly Multiplexed Microhaplotype Amplicon Panel for Plasmodium vivax
    A. Hubbard, E. A. Solares, L. Bradley, and 6 more authors
    The Journal of Infectious Diseases, 2026
  3. Genome Res.
    miRNA-like secondary structures in maize (Zea mays) genes and transposable elements correlate with small RNAs, methylation, and expression
    Galen T. Martin, Edwin A. Solares, Jeanelle Guardado-Mendez, and 3 more authors
    Genome Research, 2023
  4. PNAS
    Sex-linked gene traffic underlies the acquisition and loss of sexually dimorphic UV color vision in Heliconius butterflies
    Mahul Chakraborty, A. Guadalupe Lara, A. Dang, and 9 more authors
    Proceedings of the National Academy of Sciences, 2023
  5. G3
    Insights into the domestication of avocado and potential genetic contributors to heterodichogamy
    Edwin A. Solares, Abraham Morales-Cruz, Rosa Figueroa Balderas, and 6 more authors
    G3: Genes, Genomes, Genetics, 2023
  6. BMC Bioinf.
    HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly
    Edwin A. Solares, Y. Tao, A. D. Long, and 1 more author
    BMC Bioinformatics, 2021
  7. Nat. Plants
    The population genetics of structural variants in grapevine domestication
    Yongfeng Zhou, Andrea Minio, Mélanie Massonnet, and 5 more authors
    Nature Plants, 2019
  8. G3
    Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing
    Edwin A. Solares, Mahul Chakraborty, Danny E. Miller, and 5 more authors
    G3: Genes, Genomes, Genetics, 2018